However, ratios between c-fos expressing serotonergic (TPH) and c-fos expressing GABAergic neurons is not changed due to anxiety in Wt (Wt naïve 2.77±0.33, Wt anxiety 2.79±0.19, p = 0.372) as well as in 5-HT1A(-/-) mice (1A-ko naïve 4.11±0.27, 1A-ko 24.76±0.36, p = 0.238) (Fig 1E). This evidence concerns the gene FOS and Anxiety.