In our study, serum t PSA level, NT, TT, DD levels were measured in patients diagnosed with prostate cancer and in healthy subjects at the Medicalpark Gaziantep Hospital Urology Clinic and Disulphide / NT, Disulphide / TT, NT / TT ratios were calculated to find Dynamic Thiol / Disulphide homeostasis levels for the purpose of investigating whether it has predictive value in differentiating Prostatitis-Prostate Cancer and diagnosing Prostate Cancer and its value in predicting prognosis. This evidence concerns the gene KLK3 and Familial prostate cancer.