ATP6AP2 and cyst: 2006; Cao and Feng 2013; Seva Pessoa et al. 2013; Sihn et al. 2013; Danser 2015; Ramkumar and Kohan 2016a,b; Peters 2017). There is robust and uniform PRR expression on the apical membrane of cyst epithelium in 11 weeks old Aqp2CreTsc2 mice (Fig. 4E, right panel) and parallels the H+‐ATPase expression pattern, as does the PRR expression in the 5‐week old Aqp2CreTsc2 mice (Fig. 4E, middle panel). PRR expression in control animals is shown for comparison (Fig. 4E, left panel).