This may be explained by the following multiple factors: First, preoperative hemodynamic changes may enhance the risk of renal dysfunction in cases of liver cirrhosis by impairment of renal perfusion through immune-mediated vasodilatation, parietal and renal parenchymal edema, hypoalbuminemia, and renin-angiotensin-aldosterone axis disturbances that lead to intravascular hypovolemia. Here, REN is linked to cirrhosis of liver.