There are several bacteria that are involved in the biofilm of cystic fibrosis, wounds, contact lenses, orthopaedic implants, breast implants, dental biofilm, pacemakers, prosthetic heart valves etc. and have similar protein to M.tb PpiB.48 Our results can be extrapolated to test the efficacy of cyclosporine-A or acarbose or GaNP in reducing the dosage of other drugs or for diseases caused by biofilm-forming microorganisms as well. This evidence concerns the gene PPIB and cystic fibrosis.