42 Cyclosporine-A in combination with azole antifungal flucanizole has been shown to be effective against biofilms formed by C.albicans43 and also imparts sensitivity to C.albicans towards fluconazole by involving multiple pathways.44 GaNP is known to facilitate phagosome maturation, inhibit growth of M.tb in macrophages, inhibit HIV infection through release of interferons and can be targeted to human macrophages infected with both M.tb and HIV.45,46 These studies support our results and point to the possibility that GaNP would be an effective intervention against bacterial biofilms. The gene discussed is MCM3AP; the disease is HIV infectious disease.