TREX1 and invasive carcinoma: In another dataset from GEO (GSE9750), we observed that TREX1 mRNA expression was up regulated in invasive carcinomas (n = 33) and cervical cancer cell lines (n = 8) when compared with age-matched normal cervical tissues from hysterectomy specimens (n = 19)35 (Fig. 5C; p = 0.0019).