These lentiviral vectors (Lenti-sgNT-Myc, Lenti-sgPten-Myc, and Lenti-sgRb1-Myc) were injected intraductally into WB1P-Cas9 females (Fig. 2e) resulting in tumor formation with high penetrance and very short latency (70, 30, and 52 days after injection, respectively; n = 14, 12, and 14, respectively, Fig. 2f). The gene discussed is MYC; the disease is neoplasm.