TWIST1 and hepatocellular carcinoma: To clarify the promotion effect of the Twist1–TP transcriptional pattern on HCC VM formation and metastasis, we divided the 306 cases of clinical HCC specimens into four groups of Twist1/TP (−/−), Twist1/TP (−/+), Twist1/TP (+/−), and Twist1/TP (+/+) and analyzed the correlations between Twist1/TP and HCC characteristics.