ICAM1 and coronary artery disorder: The pooled result showed that the ICAM-1 gene E469K polymorphism was significantly associated with an increased risk of CHD (OR = 1.20, 95% CI = 1.11–1.29, for the allele K versus allele E; OR = 1.66, 95% CI = 1.43–1.92, for the K allele carriers versus EE).