VDAC1 and neurodegenerative disease: As VDACs function as pro- and anti-apoptotic elements and decide the fate of the cell (Naghdi et al., 2015; Hoogerheide et al., 2017; Magrì et al., 2018), VDAC inhibitors are purported to represent broad spectrum therapeutics for various neurodegenerative diseases (Smilansky et al., 2015; Magri and Messina, 2017).