The study aims to find a significant difference in efficacy using levels of HbA1C, among patients of Anuradhapura, Sri Lanka, who were on oral anti-diabetic regimes with and without DPP4Is; pancreatic amylase and lipase were used to compare the risk of pancreatitis; aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were used to compare the risk of hepatitis. This evidence concerns the gene GPT and pancreatitis.