No differences in the induction of CD54 were observed between vesicles (MPs and MPs-ICs) in patients with RA and SLE (Additional file 4: Figure S4D); consequently, the effect of these extracellular vesicles was studied regardless of the source, and although all experiments were performed independently for MPs and MPs-IC in each disease, in the present paper they are shown together. The gene discussed is ICAM1; the disease is systemic lupus erythematosus.