Several proteins, namely, lysozyme-C, lipocalin 1, lactoferrin, lysozyme proline-rich protein 4 (LPRR4), lysozyme proline-rich protein 3 (LPRR3), nasopharyngeal carcinoma associated PRP4 and α-1 antitrypsin in addition to few other proteins were decreased in tears of disease patients (DED, SS, MGD) in multiple studies (22,23,80,81). The gene discussed is LYZ; the disease is synovial sarcoma.