In the 524 uterine corpus endometrial carcinomas in the TCGA study, one 57‐year‐old woman harbored both a heterozygous germline hotspot missense variant (p.Asp1810Asn) and a heterozygous germline canonical splice‐site variant (c.4206+1G>C); her uterine cancer contained these two germline variants but lacked an additional somatic DICER1 variant. Here, DICER1 is linked to uterine cancer.