PTEN and ovarian serous adenocarcinoma: For example, LOH is highly correlated with defects in BRCA1/2, PTEN, FANCM and RAD51C.81 A high TAI score indicates DNA repair defects in BRCA1/2 wild‐type serous ovarian cancers.82 All BRCA1/2‐mutated tumours had high LST scores.