In this study of more than 1500 patients with CAD, a genetic risk score was created from SNPs of 3 inflammation-related genes (IL-6R rs7529229 T/C, HNF1A rs7310409 G/A, and COX-2 rs5277 G/C) and all these genes are reported to be involved in the pathogenesis of CAD. This evidence concerns the gene IL6R and coronary artery disorder.