There was no obvious evidence for rs859 related to lung squamous cell carcinoma risk (Supplementary Table S4), TNM staging (Supplementary Table S5), and lymph node metastasis (Supplementary Table S6); however, CYP24A1 rs4809957 appeared to be correlated with TNM staging and lymph node metastasis of lung cancer in different genetic models (P > 0.05; Supplementary Table S5-S6). The gene discussed is CYP24A1; the disease is metastatic malignant neoplasm in the lymph nodes.