In addition, two new genes, namely, Cflar and Ppargc1a, which showed reverse patterns of expression between the acute and chronic phases (Cflar: CASP8 and FADD-like apoptosis regulator, expression decreased from 2.442 times during the acute phase to 0.935 times during the chronic phase; Ppargc1a, expression changed from 0.216 times during the acute phase to 0.763 times during the chronic phase), although not significant, can be studied as novel targets associated with changes in muscle atrophy after rotator cuff tear or repair. This evidence concerns the gene PPARGC1A and rotator cuff syndrome.