MCL1 and B-cell chronic lymphocytic leukemia: In addition, phase I trials are actively recruiting or soon to recruit patients for testing the MCL-1 specific inhibitors S64315 (MIK665) in patients with R/R DLBCL and multiple myeloma, AML, and myelodysplastic syndrome (NCT02992483, NCT02979366, and NCT03672695) and AZD5991 in patients with R/R hematologic malignancies, CLL, T-cell lymphoma, and multiple myeloma (NCT03218683).