We previously showed that CCI-007 affects the survival of MLL-r leukemia cells by reverting the disease-driving MLL-r leukemia gene-expression signature and reducing the mRNA expression levels of HOXA9, MEIS1, CMYC, and BCL2, followed by a decrease in protein levels of these important disease drivers within three hours of exposure [10]. Here, KMT2A is linked to leukemia.