Interestingly, when we knocked down the expression of hsa_circ_001783, the proliferation, colony formation, and invasion abilities of breast cancer cells were suppressed, accompanied with the reduced expression of the miR-200c-3p targeted genes such as ZEB1/2 (refs. 32,33) and ETS1 (refs. 34,35), which are related to breast cancer proliferation and metastasis. The gene discussed is ZEB1; the disease is breast cancer.