CASP2 and neoplasm: Interestingly, the pathways melanogenesis and Wnt signaling were identified in the DEGs from both [EμMyc/Casp2−/− v EμMyc] (Fig. 7c, Supplementary Table S8d) and [Th-MYCN/Casp2−/− v Th-MYCN] (Fig. 5d) tumor comparisons.