We found that amongst the mechanisms analyzed, antibody blocking of TRAIL, led to reduced cytotoxicity towards A549 and H460 cells, but not 137 cells (Fig. 4b), whereas blocking of FasL and IFNγ had no significant effect on DNT-mediated lysis of three lung cancer cell lines analyzed (Fig. 4a and Additional file 1: Figure S3a). This evidence concerns the gene IFNG and lung cancer.