In contrast, ADRA2A, CFD, MT3, NGFR, NTN1, OSCAR, PRRX2, SPP1, TP53I11, and WFDC1 were statistically upregulated in human Sertoli cells of SCOS patients compared to OA patients (Fig. 3b). This evidence concerns the gene PRRX2 and small cell osteogenic sarcoma.