To explore the UPR in TMUV-infected DF-1 cells, expression of target genes related to the three UPR pathways was assessed, and the results showed that the IRE1 pathway was activated during the middle stage of infection (24 h postinfection) and that the ATF6 pathway was slightly activated in the late stage of infection (48 h post-infection). This evidence concerns the gene ATF6 and infection.