AZGP1 and obesity due to melanocortin 4 receptor deficiency: Many works documented the alteration in serum concentrations of ZAG was closely linked with dyslipidemia in various endocrine metabolic disorders, such as type 2 diabetes mellitus, polycystic ovary syndrome, growth hormone deficiency, Cushing’s syndrome, obesity, non-alcoholic fatty liver disease and metabolic syndrome [25–31].