Furthermore, plasma miR-144 and miR-33 levels were seen to be increased in coronary artery disease (CAD) patients [20,21], miR-155 was seen to inhibit transformation of macrophages into foam cells by targeting CEH expression [22], and miR-181b was found to be overexpressed in human atherosclerotic plaques and abdominal aortic aneurysms, where it downregulated expression of the tissue inhibitor of MMP-3, and elastin [23]. The gene discussed is ELN; the disease is coronary artery disorder.