Furthermore, there is growing evidence for diagnostic analysis of IBD-associated autoantibodies of the immunoglobulin gamma (IgG) or alpha (IgA) isotypes, e.g., against luminal antigens, such as glycoprotein 2 (GP2), to differentiate UC from CD patients, as well as distinct clinical phenotypes in CD [5]. The gene discussed is GP2; the disease is inflammatory bowel disease.