Recent TME studies investigating biomarkers in the CNS and cerebrospinal fluid of mice identified CCL5 (RANTES), CXCL9 (MIG), and CXCL10 (IP10) as being strongly upregulated in the chronic phase, which resembles chemokine expression patterns observed in MS patients [70]. The gene discussed is CXCL10; the disease is myeloid sarcoma.