This in turn suggests that the progressive accumulation of oxidant molecules during the tumor growth may well contribute to inhibit the anti-tumor immune response thus participating to the well-known “tumor immune escape”; in turn suggesting that one possible approach to trigger a proper anti-tumor immune response might be to drastically reduce the production and accumulation of oxidants due to the tumor growth, possibly stimulating the body release of an anti-oxidant molecules such as SOD-1 and GSH, as our study strongly suggests. Here, SOD1 is linked to neoplasm.