The NIR imaging probe cetuximab, an antibody against epidermal growth factor receptor (EGFR), and trastuzumab, an antibody against human epidermal growth factor receptor 2 (HER2), were labeled with a fluorophore (IRDye 800) and studied to determine their ability to detect tumor metastases within SLNs in a mouse model. The gene discussed is EGFR; the disease is neoplasm.