IREB2 and atrial fibrillation: Other interesting S-MultiXcan findings were CLCC1 (pvalue = 1.2 × 10−7, a gene for chloride channel activity); IREB2 (p-value = 2.1 × 10−7, recently linked to pulmonary conditions, [26]), and ADAM15 (p-value = 2.5 × 10−07, from the disintegrin and metalloproteinase family, linked to atherosclerosis [27], atrial fibrillation [28], and other vascular processes [29, 30]).