TCGA analysis revealed four tumour groups:96 group 1, EEC with somatic inactivating mutations in POLE exonuclease and very high mutation rates (hypermutated) (7%); group 2, EEC with microsatellite instability (MSI), frequently with MLH‐1 promoter hypermethylation and high mutation rates (28%); group 3, EEC with low copy number alterations (39%), also called EEC with no specific molecular profile; and finally, group 4 (serous‐like or copy‐number high) (26%), with a low mutation rate but frequent TP53 mutations. This evidence concerns the gene TP53 and neoplasm.