GFAP and central nervous system cancer: Since then, GFAP is often used to mark cells with stem cell characteristics in glioma and to target neural stem cells to induce gliomagenesis in animal models (Kwon et al., 2008; J. Chen et al., 2012; Bradshaw et al., 2016; Guichet et al., 2016; Kanabur et al., 2016; Jiang et al., 2017; Welker, Jaros, An, & Beattie, 2017).