Nevertheless, the observation of a decreasing number of GFAP positive cells with increasing astrocytoma grade is frequently mentioned (Cras et al., 1988; Cruz‐Sanchez et al., 1992; Gullotta et al., 1985; Oh & Prayson, 1999; Royds et al., 1986; van der Meulen et al., 1978; Xing et al., 2016). This evidence concerns the gene GFAP and astrocytoma (excluding glioblastoma).