GFAP and central nervous system cancer: One year later, high expression of GFAP in glioma with astrocyte characteristics, astrocytoma, was described for the first time, followed by many reports thereafter (Delpech et al., 1978; Uyeda, Eng, & Bignami, 1972; van der Meulen, Houthoff, & Ebels, 1978).