ADORA2A and glaucoma: We demonstrated that the blockade of adenosine A2A receptor (A2AR) confers neuroprotection to the retina in glaucoma models through the control of microglia responsiveness (Boia et al., 2017; Boia, Ambrósio, & Santiago, 2016; Madeira et al., 2016; Madeira, Elvas, et al., 2015; Santiago et al., 2014).