Similarly, the “NFkB” molecular subgroup displayed a unique BCL2-family profile within MM samples, highlighted by the overexpression of BCL2L2, BMF, and BCL2L11. Given that this subgroup is characterized by an elevated expression of NFkB targets, it is tempting to speculate that the NFkB pathway regulates these genes in MM, as it has been previously described for BCL2L2 in B cell lymphoma (52). This evidence concerns the gene NFKB1 and Miyoshi myopathy.