ITLN1 and obesity due to melanocortin 4 receptor deficiency: Previous studies reported that obesity ( Yang et al., 2006; Shibata et al., 2012) and type 2 diabetes (Tan et al., 2010) are associated with decreased omentin levels, however aerobic training (AT) (Saremi et al., 2010; Wilms et al., 2015) increases the concentration of omentin-1.