Increasingly, deep sequencing approaches on a wider variety of tumors are identifying less frequent RET rearrangements in other cancer types including chronic myelomonocytic leukemia and colorectal, breast, ovarian and head and neck tumors (Ballerini et al., 2012; Kato et al., 2017; Gozgit et al., 2018; Mulligan, 2018; Paratala et al., 2018; Pietrantonio et al., 2018; Skalova et al., 2018). Here, RET is linked to chronic myelomonocytic leukemia.