F5 and preeclampsia: The evaluation of thrombophilic genes methyle netetrahydrofolate reductase (MTHFR) and FVL in 92 mother/father/child triads revealed an increased risk only in mothers carrying two mutated copies of MTHFR and one mutated allele in FVL. Therefore, the risk of preeclampsia is not increased in the presence of fetal MTHFR or FVL mutations (Vefring et al., 2004).