Furthermore, VILIP-1 oxidation is associated with amyotrophic lateral sclerosis (ALS), since VILIP-1 is a part of the ALS-specific protein aggregates, whereas its soluble dimers are enriched in spinal cord of the animals with experimental ALS and their formation generally correlates with the disease progression (Liebl et al., 2014). This evidence concerns the gene VSNL1 and amyotrophic lateral sclerosis.