Patients from consanguineous families can still present with compound heterozygous mutations: Patients P10 and P95, issued form consanguineous Lebanese families, were for instance shown to carry respectively two compound heterozygous mutations in MYO15A responsible for an autosomal recessive type of deafness (OMIM #600316) and in SPG11 responsible for spastic paraplegia type 11 (OMIM #604360). Here, SPG11 is linked to deafness.