Here, a thorough analysis of the regulatory network revealed an extremely high degree of hsa-miR-142, hsa-miR-582, hsa-miR-590, hsa-miR-4659a, hsa-miR-548f, hsa-miR-548 g, hsa-miR-5582, GNAQ, TMTC2, and BEND2, indicating that these miRNAs and mRNAs may play key roles in the development of PD. The gene discussed is TMTC2; the disease is Parkinson disease.