CCN2 and myopia: The vitreal level of CTGF was significantly higher in the high myopia group (220.1 ± 81.3 pg/ml) than in the VMID group (170.4 ± 47.7 pg/ml, P < 0.01); in the subgroup analysis, vitreal CTGF was significantly higher in group A than in the other three subgroups (Fig. 1a).