There are many subtypes of hereditary amyloidosis caused by different amyloidogenic mutations in genes coding various proteins that include transthyretin (causing ATTR), apolipoprotein AI and AII (causing AApoAI and AApoAII amyloidosis, respectively), gelsolin (AGel), lysozyme amyloidosis (ALys), cystatin C amyloidosis (ACys), fibrinogen Aα-chain (AFib), β2-microglobulin (Aβ2M), apolipoprotein CII and CIII (causing AApoCII and AApoCIII, respectively) [2, 3]. The gene discussed is LYZ; the disease is hereditary amyloidosis.