SPDEF and infection: Using the Search Tool for the Retrieval of Interacting Genes/Proteins database, we identified further Stat6 associated proteins among the ones that were upregulated in the array (Figure 6(a, b)), and finally qPCR on individual mice confirmed that Spdef and Stat6 were upregulated during clearance of infection (p < 0.05, p < 0.01 Figure 6(c)).