Remarkably, the Foxp3YFP-Cre/YOgtfl/YRosa26Stat5b-CA/wt mice with STAT5B-CA overexpression specifically in OGT-deficient Treg cells alleviated skin inflammation (Fig. 7a), reduced sizes of the LNs and spleen (Fig. 7b), and prolonged lifespan (Fig. 7c), when compared to Foxp3YFP-Cre/YOgtfl/Y mice. The gene discussed is OGT; the disease is dermatitis.