Also absent were mutations in POLE, PTCHD2/DISP3, and DMXL2, which were recently reported in a study of Asian patients with mucosal melanoma of the oral cavity23, while 3 cases (7%) carried PTPRD mutations (P823S, T1246M, and V634fs), as reported in the same study (Supplementary Data 2). The gene discussed is POLE; the disease is mucosal melanoma.