Further exploiting the ChIP-seq data, we next modeled the potential interaction of active H3K27ac and H3K4me3 chromatin marks from the 4q13 SCPP gene cluster and the NR4A3 gene locus as a result of the genomic rearrangements for three individual tumor samples AciCC3, AciCC1 and AciCC2, representing the three different breakpoint patterns, respectively, (Fig. 4). Here, NR4A3 is linked to neoplasm.