GJA1 and Arrhythmogenic right ventricular dysplasia: Additionally, in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), Yoshida et al. detected the expression of plakoglobin and connexin 43 in myocardial biopsy specimens and confirmed the correlations between the levels of these 2 proteins and the development of ARVC, indicating that plakoglobin and connexin 43 are two specific biomarkers of arrhythmic events in ARVC [23].