Therefore, the present study was then designated to identify the changes of metabolites in the rat endometriosis models treated with GZFLC and to explore the effects of GZFLC on the levels of TGF-β1 and the mRNA expression levels of vascular endothelial growth factor (VEGF) in the endometriotic tissues. The gene discussed is TGFB1; the disease is endometriosis.